HEP10, Pooled Human Cryopreserved Hepatocytes

Description

Get the convenience, affordability, and power of a pooled population of hepatocytes in a single vial. HEP10 Pooled Human Hepatocytes are a representative population of 10 different donor hepatocytes that have been isolated using our novel patent-pending CellStream Isolation Technology™, helping to deliver consistent, predictable results in your drug metabolism studies and other biological assays.

• Pure, highly viable hepatocytes isolated using our CellStream Isolation Technology™
• 10 donor hepatocytes, 5 male and 5 female in each vial
• Verified enzymatic and pathway activity

CellStream Isolation Technology
HEP10™ Pooled Human Hepatocytes are made using our novel patent-pending CellStream Isolation Technology™. This process eliminates the disadvantages of density gradient fractionation prior to cryopreservation of the pool. Instead, we gently isolate and purify the pre-screened, high-viability, and metabolically-active hepatocytes from other cells and debris. The result is a remarkably pure pooled hepatocyte preparation with high viability for use in drug metabolism studies and other biological assays.

10 Donors in One Vial
Each vial of HEP10™ Pooled Human Hepatocytes contains hepatocytes from ten individual donors, 5 female and 5 male donors. Custom HEP10 lots can also be prepared from our broad array of high-quality, single-donor cells. Large lots are also available for extensive studies.

Verified Activity
Each pool is characterized for CYP1A2, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, CYP3A4, CYP3A4⁄5, FMO activity, and NTCP, OATP1B3, and OATP transporter pathways.

Ready for Your Drug Metabolism Experiments
HEP10 Pooled Human Hepatocytes are useful in a wide variety of applications, including intrinsic clearance, transport, toxicology, biochemistry and cell biology studies.,

Note:
These products require shipment in LN2 vapor dewars therefore additional fees may apply.

Specifications

Cell Passage Number:	Passage 0
Cell Type:	Hepatocytes
Culture Type:	Suspension Cell Culture
Donor Source:	Pooled
Form:	Cryopreserved
Format:	Tube(s)
Number of Cells:	4-8 x 10⁶
Product Line:	Gibco®
Product Size:	1.5 mL
Species:	Human

Contents & storage

Vials of cryopreserved hepatocytes should be stored in a cryostorage dewar or -135°C freezer.

Note:
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